Quantum dots have recovered the effectiveness of antibiotics without causing adverse side effects.
When it comes to the application of quantum dots, you can imagine two things: One is the screen of televisions, the other are solar panels.
Recently, however, scientists at the University of Colorado, USA have also demonstrated that quantum dots can be used to restore the effects of current antibiotics, which are gradually being resisted by viruses. .
Specifically, when illuminating excitation light into microscopic nanocrystals, they are able to exhibit quantum properties to lower the defenses of E. coli and Salmonella. Once the virus defense is lowered, antibiotics can effectively destroy them like they have never been.
Antibiotic resistance is a phenomenon that occurs when germs or bacteria are not destroyed by antibiotics. They not only exist but also produce new generations of bacteria, also have resistance to chemicals and chemicals to treat infections.
Bacteria resist antibiotics in many ways. They form defensive mechanisms such as changing the permeability characteristics of cell membranes, using pumping channels to pump antibiotics out of the body. Some pathogens have the ability to disguise the target and some even attack the antibiotic.
However, the antimicrobial mechanisms of the virus can be neutralized by quantum dots. This has been demonstrated by scientists from the University of Colorado. In their experiments, they combined antibiotics with specially selected quantum dots.
Thereafter, the drug and quantum dots mixture is activated by light with a separate wavelength. Light causes quantum dots to produce oxidative radicals, disrupting the metabolism and normal processes in bacteria.
Quantum dots act as a wind punch in boxing. After that, antibiotics will do its usual job of destroying bacteria with normal mechanisms.
“We have developed a 1-2-knock punch [for the virus],” said Associate Professor Prashant Nagpal from the University of Colorado Biochemistry Agency. “The natural reactions of bacteria to counteract [quantum dots] really make them easier to destroy.”
The results of the study published in Science Advances show that the presence of quantum dots has recovered the effectiveness of antibiotics, while not causing adverse reactions.
Associate Professor Anushree Chatterjee, another co-author of the study, said: “This is a new strategy that can counteract the pathogens that cause stronger infections than usual, and replace antibiotics.”
The discovery of the new effect of quantum dots is important, in the context of complicated antibiotic resistance worldwide.
Each year, the United States and Europe alone have about 50,000 deaths due to infection without cure. A project funded by the British government called “Antibiotic Resistance Assessment Program” estimates the total number of deaths of this type in the world at 700,000 people per year. In 2050, the number will be up to 10 million with the current rate of antibiotic resistance developing.