The biofilm of bacteria is destroyed when exposed to a sulfur-containing compound in garlic.
Garlic can prevent antibiotic-resistant viruses in hospitals, according to a new study published in Nature Scientific Reports. Specifically, a sulfur-containing compound called ajoene in garlic is capable of weakening bacterial populations, allowing antibiotics to work again.
Research done by Danish scientists points out that garlic disrupts the activity of a gene that bacteria need to stick to human tissue. Without them, bacteria cannot thrive and pose a threat.
Researchers hope to discover that garlic can help us treat cystic fibrosis and persistent ulcers in diabetics. It can also address antibiotic resistance of bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and other common infections in hospitals.
About 30% of us carry Staphylococcus aureus bacteria right on our skin or in our nostrils. This bacterium is resistant to most common antibiotics. Under normal conditions, it does not cause symptoms. But an MRSA infiltrates the blood and releases toxins, which can kill up to a fifth of infected patients.
Allow your body to fight infection
In their new study, scientists from the University of Copenhagen found that ajoene, a compound in garlic, was able to block a bacterial gene. This process leads to the destruction of their biofilms, which are bacteria used to stick to human tissue.
Although this does not kill bacteria, it prevents them from communicating with other bacteria, an activity necessary for them to multiply into populations. If so, the ajoene finally allows the body’s antibiotics and immune system to fight bacteria more effectively.
Professor Tim Holm Jakobsen, the lead author of the study, said: “We really believe that this approach can lead to treatments for patients with a poor prognosis.”
“Chronic infections like cystic fibrosis are very difficult to cure. But now, we, along with a private company, have enough theories to develop drugs that treat it from garlic and test it on patients, ”said Professor Jakabsen.
“The two types of bacteria we study are very important. They are called Staphylococcus aureus and Pseudomonas aeruginosa. Garlic compounds can resist both at the same time, and therefore can prove it a brand name. fruits when used in combination with antibiotics “.
The findings are published in Nature Scientific Reports. In fact, Staphylococcus aureus and Pseudomonas aeruginosa are among the top 12 most dangerous bacteria published by the World Health Organization earlier this year, calling for the discovery of new drugs to destroy them.
Test garlic medicine
Since 2005, there have been studies showing garlic’s ability to inhibit bacteria. By 2012, scientists began to understand the origin of this effect from ajoene compound.
Previous studies have also shown that garlic provides a strong and natural resistance to bacteria.
In 2012, a patent was issued for the use of ajoene to combat infection. Neem Biotech, a pharmaceutical company, later acquired the license to use the patent from scientists. Since then, they have produced a drug with NX-AS-401 code, to treat cystic fibrosis.
This drug will be clinically tested within the next two years.